The DHCR24 Antibody (N-term) from MyBioSource.com is a Rabbit Polyclonal antibody to Seladin 1. This antibody recognizes Human, and Mouse antigen. The DHCR24 Antibody (N-term) has been validated for the following applications: ELISA, and Western Blot.
Description
DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of its gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells